Ozone sensors in the pharmaceutical industry |
Posted: November 10, 2022 |
In pharmaceutical production, GMP regulations have extremely strict requirements for the production of pharmaceuticals (especially sterile products). For this reason, pharmaceutical production plants need to be disinfected by ozone to ensure the pharmaceutical production environment. Ozone disinfection is more effective than traditional disinfection methods.
Ozone not only effectively kills bacteria such as Pseudomonas aeruginosa, Escherichia coli and hepatitis virus, but also effectively kills viruses, so it can be said that the role of ozone disinfection in pharmaceutical production is becoming more and more important. Ozone sensors are mainly used in clean rooms of biopharmaceuticals. Biopharmaceutical cleanrooms generally have high requirements for environmental health conditions, so not only do they need to be well sealed, but they also need to be thoroughly disinfected.
The earlier disinfection method used in biopharmaceutical cleanroom is by spraying or fumigating chemicals for disinfection, however, this method often produces a lot of fine dust, which has a great impact on the cleanroom environment and is also more troublesome to implement. Therefore, with the development of a large number of new disinfection technologies in recent years, clean and sanitary ozone began to be widely used in pharmaceutical sterilization, and ozone sensors are therefore more widely used. 1. The principle of ozone disinfection Ozone is structurally unstable at room temperature and pressure, and quickly decomposes itself into oxygen and individual oxygen atoms, which are very active and have an oxidizing effect on bacteria. Ozone oxidizes and decomposes the enzymes necessary for the internal oxidation of bacteria, thus destroying their membranes and killing them, and the excess oxygen atoms will recombine themselves into ordinary oxygen molecules without any toxic residues, so it is called a non-polluting disinfectant, which is not only effective against various bacteria ( It not only has a strong ability to kill all kinds of bacteria (including hepatitis virus, Escherichia coli, green thick bacillus and miscellaneous bacteria, etc.), but also very effective in killing mold. 2. The working principle of ozone sensor ?Electrochemical principle Electrochemical detection principle, mainly by measuring the target gas into the sensor inside, in the induction electrode when the chemical reaction generated by the size of the current, so as to achieve the purpose of detecting its concentration. The electrochemical sensor is actually a fuel cell element consisting of a sensing electrode and a negative electrode, which requires no maintenance and is stable over time. In addition, City Technology's ozone sensors have high resolution and fast response time, and have technical support staff available to provide application guidance services. ?Semiconductor Semiconductor ozone sensors use gas-sensitive semiconductor materials, such as WO3, Sn0, In203 and other pieces of oxides made of sensitive components, when they absorb ozone, redox reactions occur, generating or releasing heat, so that the temperature of the component changes accordingly, so that the resistance changes, the concentration of ozone into an electrical signal to measure the ozone concentration, in general, as the concentration of the proposed In general, as the concentration of ozone increases, the resistance of the element increases significantly, within a certain range, in a linear relationship. ? Ultraviolet principle The ozone gas analyzer using the UV absorption principle generates UV light with a stable UV light source, and the light wave filter filters out other wavelengths of UV light, allowing only 253.7nm UV light to pass through, after passing through the sample photoelectric sensor, and then arriving at the sampling photoelectric sensor through ozone absorption, and comparing the electrical signals of the sample photoelectric sensor and the sampling photoelectric sensor, according to Lambert- Beer's law for mathematical model calculation, so as to derive the ozone concentration size.
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